What are the symptoms of methadone overdose?

Body as a whole

• muscle spasticity

Respiratory

• difficulty breathing
• slow, shallow and labored breathing
• stopped breathing (sometimes fatal within 2-4 hours)

Eyes, ears, nose and throat

• pinpoint pupils
• bluish skin
• bluish fingernails and lips

Gastrointestinal

• spasms of the stomach and/or intestinal tract
• constipation

Heart and blood vessels

• weak pulse
• low blood pressure

Nervous system

• drowsiness
• disorientation
• coma